Fabrication and characterization of laponite-calcium phosphate based cement for filling bone defects

M Roozbahani, M Kharaziha, R Emadi

The aim of this study was to develop a novel nanocomposite laponite-calcium phosphate bone cement (CPC) consisting of various concentrations of laponite nanoplates (LAP). Moreover, effects of LAP on the mechanical and handling properties of CPCs were studied. Results demonstrated that the rate of converting cement reactants into hydroxyapatite significantly increased, while initial and final setting time of cement gradually decreased by incorporation of LAP. Noticeably, incorporation of 2 wt.% LAP into CPC reduced the initial and final setting time. Moreover, incorporation of 2 wt.% LAP significantly improved the mechanical properties and injectability of CPCs.